黄石博士是中南大学医学遗传学国家重点实验室教授。

遗传学学士，复旦大学生物系遗传学专业, 1979-1983；

Ph.D. Biochemistry, University of 加利福尼亚州，Davis, 1984-1988；

Postdoctoral Fellow, University of California，San Diego, 1989-1992；

Assistant Professor, The Burnham Institute for Medical Research, 1992-1998；

Associate The Professor, The Burnham Institute for Medical Research, 1998-2008；

Professor, State Key Laboratory of Medical Genetics, CSU, 2009-present。

他在解放军军事医学科学院长大，他的父亲是那里的教授。他童年的爱好开始是运动，后来是纯粹艺术。由于1978年报考中央美术学院失利，他的兴趣转向了自然科学。他1979至1983年在复旦大学获得遗传学学士。他是CUSBEA第三期（1984）公派出国留学生，于1988年获得加利福尼亚大学戴维斯分校博士学位。随后在加利福尼亚大学-圣地亚哥分校完成博士后工作，并于1992年被任命为美国圣地亚哥Burnham Institute 助理教授（assistant professor），1998年升为副教授（associate professor）。2009年回国后至今担任中南大学教授。

早年对艺术的研习培养了他的审美观，使他在自然科学研究中，更关注能发挥创造性的课题。黄石教授的实验室首先发现了RIZ肿瘤基因和PRDM家族组蛋白甲基转移酶，并确定了它通过表观遗传学调节在高肉低蔬菜饮食（西方式饮食）增加癌症患病风险中的作用。从2003年起，黄石教授开始了他对遗传和表观遗传在生物复杂性进化中相互关系的原创性研究。他在世界上首次提出了种内变异度上限理论（maximum genetic diversity theory），这一理论解决了主流进化理论不能解释分子进化中的遗传等距离现象以及不能解释复杂疾病的遗传机制这些重要问题。

1. 黄益敏，夏梦颖，黄石（2013）遗传多样性上限假说所揭示的进化历程 《遗传》，Hereditas (Beijing), 35:599-606. Yimin Huang, Mengying Xia, and Shi Huang (2013) The evolutionary process unveiled by the maximum genetic diversity hypothesis. Hereditas, 35:599-606. pdf in Chinese；

2. Zhu, Z., Lu, Q., Yuan, D., Li, Y., Man, X., Zhu, Y., and Huang, S. (2013) Role of genetic polymorphisms intransgenerational inheritance of inherent as well as acquired traits in budding yeast. arXiv:1302.7276 ；

3. Hu, T., Long , M., Yuan D., Zhu Z., Huang, Y., and Huang, S. (2013) The genetic equidistance result: misreading by the molecular clock and neutral theory and reinterpretation nearly half of a century later. Sci China Life Sci, 56:254-261 (in English). 胡涛波，龙孟平，袁德健，朱作斌，黄益敏，黄石（2013）遗传等距离结果: 分子钟和中性理论的误读及其近半世纪后的重新解谜 《中国科学：生命科学》 43: 275-282；

4. Yuan, D, Zhu, Z., and Huang, S. (2012) A more complete reinterpretation of molecular evolution nearly half of a century later supports the multiregional hypothesis rather than the out of Africa hypothesis. News magazine from the Chinese Academy of Social Sciences, Issue 389, (in Chinese). 袁德健 朱作斌 黄石 分子进化迟到近半世纪的完整解读：支持“多地区起源说”而不是“出非洲说” 《中国社会科学报》2012年12月7日第389期；

5. Yuan, D., Zhu, Z., Tan, X., Liang, J., Zeng, C., Zhang, J., Chen, J., Ma, L., Dogan, A., Brockmann, G., Goldmann, G., Medina,E., Rice, A.D., Moyer, R.W., Man, X., Yi, K., Li, Y., Lu, Q., Huang, Y., Wang, D., Yu, J., Guo, H., Xia, K., and Huang, S. (2012) Methods for scoring the collective effects of SNPs: Minor alleles of common SNPs quantitatively affect traits/diseases and are under both positive and negative selection；.

6. Huang, S. (2012) Primate phylogeny: molecular evidence for a pongid clade excluding humans and a prosimian clade containing tarsiers. Sci China Life Sci, 55: 709-725. pdf；

7. Huang, S. (2010) The overlap feature of the genetic equidistance result, a Fundamental biological phenomenon overlooked for nearly half of a century. Biological Theory, 5: 40-52. pdf；

8. Huang, S. (2009) Inverse relationship between genetic diversity and epigenetic complexity. Preprint available, Nature Precedings；

9. Huang, S. (2009) Molecular evidence for the hadrosaur B. canadensis as an outgroup to a clade containing the dinosaur T. rex and 巴尔的摩金莺队 Rivista di Biologia / Biology Forum, 102: 20-22. pdf；

10. Huang, S. (2008) The genetic equidistance result of molecular evolution is independent of mutation rates. J. Comp. Sci. Syst. Biol., 1: 92-102. pdf；

11. Huang, S. (2008) Ancient Fossil specimens are genetically more distant to an outgroup than extant sister 物种 are. Rivista di Biologia / Biology Forum, 101: 93-108. pdf；

12. Huang, S. (2008) Histone methylation and the initiation of cancer. Cancer Epigenetics, Ed. Tollefsbol, T., CRC Books. pdf；

13. Zhou, W., alonso, S., Takai, D., Lu, S.C., Yamamoto, F., Perucho, M., and Huang, S. (2008) Requirement of RIZ1 for cancer prevention by 甲基balanced diet. PLoS One, 3: e3390. doi:10.1371/journal.pone.0003390. pdf；

14. Deng, Q. and Huang, S. (2004) PRDM5 is silenced in human cancers and has growth suppressive activities. Oncogene. 23, 4903-4910.；

15. Carling, T., Kim, K.-C., Yang, X., Gu, J., Piao, Z., Zhang, X., and Huang, S. (2004) A histone methyltransferase is required for maximal response to female sex hormones. 摩尔 Cell. Biol., 24, 7032-7042；

16. Kim, K.-C., Geng, L., and Huang, S. (2003). Inactivation of a histone methyltransferase by mutations in human cancersCancer Res, 63, 7619-7623；

17. Huang, S. (2002).Histone methyltransferases, diet nutrients and tumor suppressors. Nature Reviews Cancer, 2, 469-476.pdf；

18. Steele-Perkins, G., Fang, W., Van Gele, M., Yang, X.-H., Gu, J., Carling, T., Buyse, I. M., Fletcher, J. A., Liu, J., Bronson, R.T., Chadwick, R.B., de la Chapelle, A., Zhang, X-k., Speleman, F., and Huang, S. ；(2001). Tumor formation and inactivation of RIZ1, a 上海曼伦商贸有限公司binding member of a NU.CLEAR protein methyltransferase 总科 Genes dev 15: 2250-2262.   ；

CUSBEA Scholar, Class III, 1984；

Pew Scholar in the Biomedical Sciences, 1993；

Furong Scholar 芙蓉学者, 2010。